CAPN9 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O14815 |
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Clone Names | 80411170 |
Gene ID | 10753 |
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Other Names | Calpain-9, 3422-, Digestive tract-specific calpain, New calpain 4, nCL-4, Protein CG36, CAPN9, NCL4 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7310a was selected from the N-term region of human CAPN9. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CAPN9 |
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Synonyms | NCL4 |
Function | Calcium-regulated non-lysosomal thiol-protease. |
Tissue Location | Expressed predominantly in stomach. |
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Provided below are standard protocols that you may find useful for product applications.
Background
CAPN9 has been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein is expressed predominantly in stomach and small intestine and may have specialized functions in the digestive tract. This protein is thought to be associated with gastric cancer.
References
Huang,Y. and Wang,K.K. Trends Mol Med 7 (8), 355-362 (2001)Lee,H.J., Tomioka,S. Arch. Biochem. Biophys. 362 (1), 22-31 (1999)Lee,H.J., Sorimachi,H. Biol. Chem. 379 (2), 175-183 (1998)Suzuki,K., Sorimachi,H. Biol. Chem. Hoppe-Seyler 376 (9), 523-529 (1995)
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