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POLE3 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9NRF9
Clone Names 80917151
Peptide ID 80917151
Additional Information
Gene ID 54107
Other Names DNA polymerase epsilon subunit 3, Arsenic-transactivated protein, AsTP, Chromatin accessibility complex 17 kDa protein, CHRAC-17, HuCHRAC17, DNA polymerase II subunit 3, DNA polymerase epsilon subunit p17, POLE3, CHRAC17
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7316a was selected from the N-term region of human POLE3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name POLE3
Synonyms CHRAC17
Function Forms a complex with DNA polymerase epsilon subunit CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1.
Cellular Location Nucleus.
Tissue Location Expressed in all tissues tested, including, heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas
Research Areas
Citations (0)

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POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.


Bolognese,F., Imbriano,C. Nucleic Acids Res. 28 (19), 3830-3838 (2000)Li,Y., Pursell,Z.F. J. Biol. Chem. 275 (30), 23247-23252 (2000)

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$ 80.00
Cat# BP7316a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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