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GSN Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P06396
Clone Names 80902106
Peptide ID 80902106
Additional Information
Gene ID 2934
Other Names Gelsolin, AGEL, Actin-depolymerizing factor, ADF, Brevin, GSN
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7326a was selected from the N-term region of human GSN. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GSN
Function Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis.
Cellular Location Isoform 2: Cytoplasm, cytoskeleton.
Tissue Location Phagocytic cells, platelets, fibroblasts, nonmuscle cells, smooth and skeletal muscle cells
Research Areas
Citations (0)

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GSN binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this protein are a cause of familial amyloidosis Finnish type (FAF).


Li,Q., Ye,Z. Biochem. Biophys. Res. Commun. 385 (2), 284-289 (2009)Walsh,N., Dowling,P. J Proteomics 71 (5), 561-571 (2008)Paunio,T., Kiuru,S. Genomics 13 (1), 237-239 (1992)

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$ 80.00
Cat# BP7326a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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