|Other Names||Glyoxylate reductase/hydroxypyruvate reductase, GRHPR, GLXR|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7331b was selected from the C-term region of human GRHPR. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate oxidizes D-glycerate to hydroxypyruvate.|
|Tissue Location||Ubiquitous. Most abundantly expressed in the liver.|
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Provided below are standard protocols that you may find useful for product applications.
GRHPR is an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The protein has widespread tissue expression and has a role in metabolism.
Levin-Iaina,N., Dinour,D. J. Urol. (2009) In pressTakayama,T., Nagata,M. Nephrol. Dial. Transplant. 22 (8), 2371-2374 (2007)Webster,K.E., Ferree,P.M. Hum. Genet. 107 (2), 176-185 (2000)Cramer,S.D., Ferree,P.M. Hum. Mol. Genet. 8 (11), 2063-2069 (1999)
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