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PITX1 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P78337
Clone Names 80703034
Additional Information
Gene ID 5307
Other Names Pituitary homeobox 1, Hindlimb-expressed homeobox protein backfoot, Homeobox protein PITX1, Paired-like homeodomain transcription factor 1, PITX1, BFT, PTX1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7334c was selected from the Center region of human PITX1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PITX1
Synonyms BFT, PTX1
Function Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb.
Cellular Location Nucleus.
Research Areas
Citations (0)
citation

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Background

PITX1 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This protein acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin.

References

Grimminger,P., Ling,F.C. Anticancer Res. 29 (4), 1281-1286 (2009)Gurnett,C.A., Alaee,F. Am. J. Hum. Genet. 83 (5), 616-622 (2008)Philippi,A., Tores,F. BMC Med. Genet. 8, 74 (2007)Shang,J., Li,X. Genomics 40 (1), 108-113 (1997)

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$ 277.78
Cat# BP7334c
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