PITX1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P78337 |
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Clone Names | 80703034 |
Gene ID | 5307 |
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Other Names | Pituitary homeobox 1, Hindlimb-expressed homeobox protein backfoot, Homeobox protein PITX1, Paired-like homeodomain transcription factor 1, PITX1, BFT, PTX1 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7334c was selected from the Center region of human PITX1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | PITX1 |
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Synonyms | BFT, PTX1 |
Function | Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb. |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
PITX1 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This protein acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin.
References
Grimminger,P., Ling,F.C. Anticancer Res. 29 (4), 1281-1286 (2009)Gurnett,C.A., Alaee,F. Am. J. Hum. Genet. 83 (5), 616-622 (2008)Philippi,A., Tores,F. BMC Med. Genet. 8, 74 (2007)Shang,J., Li,X. Genomics 40 (1), 108-113 (1997)
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