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PP11 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P21128 |
|---|---|
| Clone Names | 80703036 |
| Gene ID | 8909 |
|---|---|
| Other Names | Poly(U)-specific endoribonuclease, 31--, Placental protein 11, PP11, Protein endoU, Uridylate-specific endoribonuclease, ENDOU |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7335b was selected from the C-term region of human PP11. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ENDOU |
|---|---|
| Function | Endoribonuclease that cleaves single-stranded RNAs at 5' of uridylates and releases a product with a 2',3'-cyclic phosphate at the 3'-end. The UU and GU sites are more efficiently cleaved than CU and AU sites. |
| Cellular Location | Secreted. |
| Tissue Location | Placental-specific, but also associated with various malignant neoplasms |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
PP11 is a protein with protease activity. Its specific function has not been determined. The protein may be useful as a tumor marker.
References
Laneve,P., Gioia,U. J. Biol. Chem. 283 (50), 34712-34719 (2008)Jenne,D. Biochem. Biophys. Res. Commun. 176 (3), 1000-1006 (1991)Grundmann,U., Romisch,J. DNA Cell Biol. 9 (4), 243-250 (1990)Inaba,N., Ishige,H. Oncodev. Biol. Med. 3 (5-6), 379-389 (1982)
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