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TYR Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P14679
Clone Names 80722107
Peptide ID 80722107
Additional Information
Gene ID 7299
Other Names Tyrosinase, LB24-AB, Monophenol monooxygenase, SK29-AB, Tumor rejection antigen AB, TYR
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7345c was selected from the Center region of human TYR . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TYR
Function This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone.
Cellular Location Melanosome membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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TYR catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The protein has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this protein result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation.


Ostankovitch,M. J. Immunol. 182 (8), 4830-4835 (2009)Chintamaneni,C.D. Proc. Natl. Acad. Sci. U.S.A. 88 (12), 5272-5276 (1991)

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$ 80.00
Cat# BP7345c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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