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COL5A2 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P05997
Clone Names 80703015
Additional Information
Gene ID 1290
Other Names Collagen alpha-2(V) chain, COL5A2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7358a was selected from the N-term region of human COL5A2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name COL5A2
Function Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin. Type V collagen is a key determinant in the assembly of tissue-specific matrices (By similarity).
Cellular Location Secreted, extracellular space, extracellular matrix {ECO:0000255|PROSITE-ProRule:PRU00793}
Research Areas
Citations (0)
citation

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Background

COL5A2 is an alpha chain for one of the low abundance fibrillar collagens. Fibrillar collagen molecules are trimers that can be composed of one or more types of alpha chains. Type V collagen is found in tissues containing type I collagen and appears to regulate the assembly of heterotypic fibers composed of both type I and type V collagen. This protein is closely related to type XI collagen and it is possible that the collagen chains of types V and XI constitute a single collagen type with tissue-specific chain combinations.

References

Menon,R., Reprod. Biol. Endocrinol. 7 (1), 62 (2009)Videman,T., Arthritis Rheum. 60 (2), 470-481 (2009)Segev,F., Invest. Ophthalmol. Vis. Sci. 47 (2), 565-573 (2006)

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$ 277.78
Cat# BP7358a
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