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CATD Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P07339
Clone Names 80808013
Peptide ID 80808013
Additional Information
Gene ID 1509
Other Names Cathepsin D, Cathepsin D light chain, Cathepsin D heavy chain, CTSD, CPSD
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7368c was selected from the Center region of human CATD. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CPSD
Function Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
Cellular Location Lysosome. Melanosome. Secreted, extracellular space. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix (PubMed:20551380).
Tissue Location Expressed in the aorta extrcellular space (at protein level).
Research Areas
Citations (0)

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CATD is a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Mutations in CATD gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease.


Byun,H.O., Cancer Res. 69 (11), 4638-4647 (2009)Brujan,I., Rom J Morphol Embryol 50 (1), 31-39 (2009)

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$ 80.00
Cat# BP7368c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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