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ENDOGL1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9Y2C4 |
|---|---|
| Clone Names | 80513113 |
| Gene ID | 9941 |
|---|---|
| Other Names | Nuclease EXOG, mitochondrial, 3130-, Endonuclease G-like 1, Endo G-like 1, EXOG, ENDOGL1, ENDOGL2, ENGL |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7384a was selected from the N-term region of human ENDOGL1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | EXOG |
|---|---|
| Synonyms | ENDOGL1, ENDOGL2, ENGL |
| Function | Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5'-3' exonuclease activity. |
| Cellular Location | Mitochondrion inner membrane |
| Tissue Location | Ubiquitous. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ENDOGL1 is an endo/exonuclease with 5'-3' exonuclease activity. The enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death.
References
Cymerman,I.A., Nucleic Acids Res. 36 (4), 1369-1379 (2008)
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