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FBP1 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P09467
Clone Names 80513123
Peptide ID 80513123
Additional Information
Gene ID 2203
Other Names Fructose-1, 6-bisphosphatase 1, FBPase 1, D-fructose-1, 6-bisphosphate 1-phosphohydrolase 1, Liver FBPase, FBP1, FBP
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7385a was selected from the N-term region of human FBP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FBP1
Synonyms FBP
Function Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.
Tissue Location Expressed in pancreatic islets.
Research Areas
Citations (0)

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Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.


Visinoni,S., Am. J. Physiol. Endocrinol. Metab. 295 (5), E1132-E1141 (2008)Kebede,M., Diabetes 57 (7), 1887-1895 (2008)

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$ 80.00
Cat# BP7385a
(40 western blots)
Availability: In Stock
Bulk Size
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