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ELF5 Antibody (Center) Blocking Peptide

Synthetic peptide

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Catalog # SizeAvailability Price  
BP7394c 0.1 mg In Stock Call INQUIRE
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ELF5 Antibody (Center) Blocking Peptide - Product info

Primary AccessionQ9UKW6
Clone Names80902015

ELF5 Antibody (Center) Blocking Peptide - Additional info

Gene ID 2001
Target/Specificity
The synthetic peptide sequence used to generate the antibody AP7394c was selected from the Center region of human ELF5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Precautions
This product is for research use only. Not for use in diagnostic or therapeutic procedures.

ELF5 Antibody (Center) Blocking Peptide - Protein Information

Name ELF5
Synonyms ESE2
Function
Transcriptionally activator that may play a role in regulating the later stages of keratinocytes terminal differentiation.
Cellular Location
Nucleus (By similarity).
Tissue Location
Expressed exclusively in tissues with a high content of epithelial cells. Highly expressed in salivary gland, mammary gland, kidney and prostate. Weakly expressed in placenta and lung. Isoform 1 and isoform 2 are differentially expressed in different tissues. In the kidney, only isoform 1 was expressed, while prostate expressed both isoforms, with levels of isoform 2 being higher. Expression is up-regulated during keratinocyte differentiation. Several epithelial carcinoma cell lines showed lack of expression

ELF5 Antibody (Center) Blocking Peptide - Related products

AP7394C: ELF5 Antibody (Center)

AT1896a: ELF5 Antibody (monoclonal) (M01)

AF2269a: ELF5 Antibody (C-Term)

ELF5 Antibody (Center) Blocking Peptide - Research Areas

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Provided below are standard protocols that you may find useful for product applications.

BACKGROUND

ELF5 is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus.

REFERENCES

Choi,Y.S., Biochem. J. 398 (3), 497-507 (2006)Tummala,R., J. Cell. Biochem. 97 (4), 766-781 (2006)