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CSNK1A1 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P48729
Clone Names 2022706
Peptide ID 2022706
Additional Information
Gene ID 1452
Other Names Casein kinase I isoform alpha, CKI-alpha, CK1, CSNK1A1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7400a was selected from the C-term region of human CK1a . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CSNK1A1
Function Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May phosphorylate PER1 and PER2. May play a role in segregating chromosomes during mitosis.
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Nucleus speckle. Note=Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis
Research Areas
Citations ( 0 )


Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. CK1a can phosphorylate a large number of proteins. This cytoplasmic protein participates in Wnt signaling. It has been demonstrated to phosphorylate CTNNB1 on Ser-45 and to interact with the Axin complex.


Liu, C., et al., Cell 108(6):837-847 (2002).Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).Fish, K.J., et al., J. Biol. Chem. 270(25):14875-14883 (1995).Tapia, C., et al., FEBS Lett. 349(2):307-312 (1994).

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$ 80.00
Cat# BP7400a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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