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CSNK1E Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P49674
Clone Names 2022203
Peptide ID 2022203
Additional Information
Gene ID 102800317;1454
Other Names Casein kinase I isoform epsilon, CKI-epsilon, CKIe, CSNK1E
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7403a was selected from the C-term region of human CK1e . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phospohorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine- induced granuloytic differentiation.
Cellular Location Cytoplasm. Nucleus
Tissue Location Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. Expressed in monocytes and lymphocytes but not in granulocytes
Research Areas
Citations (0)

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CK1e is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. This protein is found in the cytoplasm as a monomer and can phosphorylate a variety of proteins, including itself. It has been shown to phosphorylate period, a circadian rhythm protein.


Hino, S., et al., J. Biol. Chem. 278(16):14066-14073 (2003). Eide, E.J., et al., J. Biol. Chem. 277(19):17248-17254 (2002). Keesler, G.A., et al., Neuroreport 11(5):951-955 (2000). Cegielska, A., et al., J. Biol. Chem. 273(3):1357-1364 (1998). Kloss, B., et al., Cell 94(1):97-107 (1998).

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$ 80.00
Cat# BP7403a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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