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LARS Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9P2J5
Clone Names 71228124
Peptide ID 71228124
Additional Information
Gene ID 51520
Other Names Leucine--tRNA ligase, cytoplasmic, Leucyl-tRNA synthetase, LeuRS, LARS, KIAA1352
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7413b was selected from the C-term region of human LARS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA1352
Function Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Exhibits a post-transfer editing activity to hydrolyze mischarged tRNAs.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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LARS, a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. This enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain.


Lue,S.W.; Biochemistry 46 (15), 4466-4472 (2007)Ling,C., J. Biol. Chem. 280 (41), 34755-34763 (2005)Giles,R.E., Somatic Cell Genet. 6 (5), 667-687 (1980)

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$ 80.00
Cat# BP7413b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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