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CAMK2A Antibody (C-term E370) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UQM7
Clone Names 80220244
Peptide ID 80220244
Additional Information
Gene ID 815
Other Names Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha, CAMK2A, CAMKA, KIAA0968
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7418b was selected from the C-term region of human CAMK2A. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms CAMKA, KIAA0968
Function CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity).
Cellular Location Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse Note=Postsynaptic lipid rafts.
Research Areas
Citations (0)

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CAMK2A belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by the gene for CAMK2A is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity.


Lee,C.W., Mol. Pharmacol. 73 (5), 1454-1464 (2008)Yuan,K., Lab. Invest. 87 (9), 938-950 (2007)

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$ 80.00
Cat# BP7418b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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