JUND Antibody (S255) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P17535 |
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Other Accession | Q53EK9 |
Clone Names | 109086 |
Gene ID | 3727 |
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Other Names | Transcription factor jun-D, JUND |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7419a was selected from the S255 region of human JUND. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | JUND |
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Function | Transcription factor binding AP-1 sites (PubMed:9989505). Heterodimerizes with proteins of the FOS family to form an AP-1 transcription factor complex, thereby enhancing their DNA binding activity to an AP-1 consensus sequence 3'-TGA[GC]TCA-5' and enhancing their transcriptional activity (PubMed:9989505, PubMed:28981703). |
Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
JUND is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis.
References
Caffarel,M.M., Oncogene 27 (37), 5033-5044 (2008)Mehraein-Ghomi,F., Prostate 68 (9), 924-934 (2008)
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