|Other Names||Apolipoprotein A-II, Apo-AII, ApoA-II, Apolipoprotein A2, Proapolipoprotein A-II, ProapoA-II, Truncated apolipoprotein A-II, Apolipoprotein A-II(1-76), APOA2|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7422c was selected from the Center region of human APOA2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.|
|Tissue Location||Plasma; synthesized in the liver and intestine|
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Provided below are standard protocols that you may find useful for product applications.
APOA2, apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia.
Duesing,K., BMC Med. Genet. 10, 13 (2009)Atta,M., Thromb. Haemost. 100 (3), 391-396 (2008)Blanco-Vaca,F., J. Lipid Res. 42 (11), 1727-1739 (2001)
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