APOA2 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P02652 |
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Clone Names | 80118120 |
Gene ID | 336 |
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Other Names | Apolipoprotein A-II, Apo-AII, ApoA-II, Apolipoprotein A2, Proapolipoprotein A-II, ProapoA-II, Truncated apolipoprotein A-II, Apolipoprotein A-II(1-76), APOA2 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7422c was selected from the Center region of human APOA2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | APOA2 |
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Function | May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. |
Cellular Location | Secreted. |
Tissue Location | Plasma; synthesized in the liver and intestine. |
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Provided below are standard protocols that you may find useful for product applications.
Background
APOA2, apolipoprotein (apo-) A-II, which is the second most abundant protein of the high density lipoprotein particles. The protein is found in plasma as a monomer, homodimer, or heterodimer with apolipoprotein D. Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia.
References
Duesing,K., BMC Med. Genet. 10, 13 (2009)Atta,M., Thromb. Haemost. 100 (3), 391-396 (2008)Blanco-Vaca,F., J. Lipid Res. 42 (11), 1727-1739 (2001)
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