|Other Names||Apolipoprotein D, Apo-D, ApoD, APOD|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7423a was selected from the N-term region of human APOD. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||APOD occurs in the macromolecular complex with lecithin- cholesterol acyltransferase. It is probably involved in the transport and binding of bilin. Appears to be able to transport a variety of ligands in a number of different contexts.|
|Tissue Location||Expressed in liver, intestine, pancreas, kidney, placenta, adrenal, spleen, fetal brain tissue and tears|
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Provided below are standard protocols that you may find useful for product applications.
APOD is a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism.
Do Carmo,S., J. Neurosci. 28 (41), 10330-10338 (2008)Chen,Y., Brain Res. 1233, 196-202 (2008)Wei,Y.J., Biomarkers 13 (5), 535-548 (2008)
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