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HIBCH Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q6NVY1
Clone Names 81020149
Peptide ID 81020149
Additional Information
Gene ID 26275
Other Names 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial, 3-hydroxyisobutyryl-coenzyme A hydrolase, HIB-CoA hydrolase, HIBYL-CoA-H, HIBCH
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7435c was selected from the Center region of human HIBCH. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA.
Cellular Location Mitochondrion.
Tissue Location Highly expressed in liver and kidney, also detected in heart, muscle and brain (at protein level). Not detected in lung.
Research Areas
Citations (0)

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HIBCH is responsible for the specific hydrolysis of HIBYL-CoA, a valine catabolite, as well as the hydrolysis of beta-hydroxypropionyl-CoA, an intermediate in a minor pathway of propionate metabolism.


Hawes J.W., Jaskiewicz J., Shimomura Y.J. Biol. Chem. 271:26430-26434(1996) Loupatty F.J., Clayton P.T.Am. J. Hum. Genet. 80:195-199(2007)

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$ 80.00
Cat# BP7435c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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Ordering Information

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