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CETP Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P11597 |
|---|---|
| Clone Names | 80325137 |
| Gene ID | 1071 |
|---|---|
| Other Names | Cholesteryl ester transfer protein, Lipid transfer protein I {ECO:0000312|MIM:118470}, CETP (HGNC:1869) |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7440a was selected from the N-term region of human CETP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CETP (HGNC:1869) |
|---|---|
| Function | Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL (PubMed:3600759, PubMed:24293641, PubMed:3281933). Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination (PubMed:17237796). |
| Cellular Location | Secreted. Note=Secreted in plasma |
| Tissue Location | Expressed by the liver and secreted in plasma. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Cholesteryl ester transfer protein (CETP) transfers cholesteryl esters between lipoproteins. CETP may effect susceptibility to atherosclerosis.
References
Nagano M., Yamashita S., Hirano K.J. Lipid Res. 43:1011-1018(2002)Morabia A., Cayanis E., Costanza M.C.Hum. Mol. Genet. 12:2733-2743(2003)Liu T., Qian W.-J., Gritsenko M.A.J. Proteome Res. 4:2070-2080(2005)
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