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CREBL2 Antibody (N-term K27) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O60519
Clone Names 81006049
Peptide ID 81006049
Additional Information
Gene ID 1389
Other Names cAMP-responsive element-binding protein-like 2, CREBL2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7441a was selected from the N-term region of human CREBL2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Probable regulator of CREB1 transcriptional activity which is involved in adipose cells differentiation. May also play a regulatory role in the cell cycle. Identification in a chromosomal region frequently deleted in various cancers suggests that it might act as a tumor suppressor.
Cellular Location Nucleus.
Research Areas
Citations (0)

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cAMP response element (CRE)-binding protein-like-2 (CREBL2) was identified in a search to find genes in a commonly deleted region on chromosome 12p13 flanked by ETV6 and CDKN1B genes, frequently associated with hematopoietic malignancies, as well as breast, non-small-cell lung and ovarian cancers. CREBL2 shares a 41% identity with CRE-binding protein (CREB) over a 48-base long region which encodes the bZip domain of CREB. The bZip domain consists of about 30 amino acids rich in basic residues involved in DNA binding, followed by a leucine zipper motif involved in protein dimerization. This suggests that CREBL2 encodes a protein with DNA binding capabilities. The occurance of CREBL2 deletion in malignancy suggests that CREBL2 may act as a tumor suppressor gene.


Hoornaert I., Marynen P., Baens M.Genomics 51:154-157(1998)Thomson D.M., Herway S.T., Fillmore N.J. Appl. Physiol. 104:429-438(2008)

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$ 80.00
Cat# BP7441a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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