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OPLAH Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | O14841 |
|---|---|
| Clone Names | 80917112 |
| Gene ID | 26873 |
|---|---|
| Other Names | 5-oxoprolinase, 5-oxo-L-prolinase, 5-OPase, Pyroglutamase, OPLAH |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7475a was selected from the N-term region of human OPLAH. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | OPLAH (HGNC:8149) |
|---|---|
| Function | Catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. |
| Cellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q75WB5} |
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Provided below are standard protocols that you may find useful for product applications.
Background
OPLAH catalyzes the cleavage of 5-oxo-L-proline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.ATP + 5-oxo-L-proline + 2 H2O = ADP + phosphate + L-glutamate.
References
Watanabe T., Abe K.Biol. Pharm. Bull. 27:288-294(2004)Bechtel S., Rosenfelder H.BMC Genomics 8:399-399(2007)
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