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GCAT Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession O75600
Clone Names 81020113
Peptide ID 81020113
Additional Information
Gene ID 23464
Other Names 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial, AKB ligase, Aminoacetone synthase, Glycine acetyltransferase, GCAT, KBL
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7498c was selected from the Center region of human GCAT. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KBL
Cellular Location Mitochondrion. Nucleus. Note=Translocates to the nucleus upon cold and osmotic stress
Tissue Location Strongly expressed in heart, brain, liver and pancreas. Also found in lung.
Research Areas
Citations (0)

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The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. GCAT is the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase.


Edgar,A.J., Polak,J.M.Eur. J. Biochem. 267 (6), 1805-1812 (2000)Tressel,T., Thompson,R., J. Biol. Chem. 261 (35), 16428-16437 (1986)

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$ 80.00
Cat# BP7498c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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