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CDC2L5 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q14004
Clone Names 3010803
Peptide ID 3010803
Additional Information
Gene ID 8621
Other Names Cyclin-dependent kinase 13, CDC2-related protein kinase 5, Cell division cycle 2-like protein kinase 5, Cell division protein kinase 13, hCDK13, Cholinesterase-related cell division controller, CDK13, CDC2L, CDC2L5, CHED, KIAA1791
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7514a was selected from the N-term region of human CDC2L5 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDK13
Synonyms CDC2L, CDC2L5, CHED, KIAA1791
Function Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at 'Lys-50' and 'Lys- 51', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.
Cellular Location Nucleus speckle
Tissue Location Expressed in fetal brain, liver, muscle and in adult brain. Also expressed in neuroblastoma and glioblastoma tumors
Research Areas
Citations (0)

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CDC2L5, a member of the CDC2/CDKX subfamily of Ser/Thr protein kinases, may be a controller of the mitotic cell cycle. This protein is involved in the blood cell development. Expression is found in fetal brain, liver, muscle and in adult brain, and also in neuroblastoma and glioblastoma tumors.


Lapidot-Lifson, Y., et al., Proc. Natl. Acad. Sci. U.S.A. 89(2):579-583 (1992).

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$ 80.00
Cat# BP7514a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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