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CDC7 (CDC7L1) Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession O00311
Clone Names 3031705
Peptide ID 3031705
Additional Information
Gene ID 8317
Other Names Cell division cycle 7-related protein kinase, CDC7-related kinase, HsCdc7, huCdc7, CDC7, CDC7L1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7515b was selected from the C-term region of human CDC7L1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDC7
Synonyms CDC7L1
Function Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.
Cellular Location Nucleus.
Research Areas
Citations (0)

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CDC7L1 is predominantly localized in the nucleus and is a cell division cycle protein with kinase activity. Although expression levels of the protein appear to be constant throughout the cell cycle, the protein kinase activity appears to increase during S phase. It has been suggested that the protein is essential for initiation of DNA replication and that it plays a role in regulating cell cycle progression. Overexpression of this gene product may be associated with neoplastic transformation for some tumors.


Montagnoli, A., et al., EMBO J. 21(12):3171-3181 (2002).Hess, G.F., et al., Gene 211(1):133-140 (1998).Jiang, W., et al., Proc. Natl. Acad. Sci. U.S.A. 94(26):14320-14325 (1997).Sato, N., et al., EMBO J. 16(14):4340-4351 (1997).

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$ 80.00
Cat# BP7515b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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