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CDKN3 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q16667
Clone Names 3011501
Peptide ID 3011501
Additional Information
Gene ID 1033
Other Names Cyclin-dependent kinase inhibitor 3, CDK2-associated dual-specificity phosphatase, Cyclin-dependent kinase interactor 1, Cyclin-dependent kinase-interacting protein 2, Kinase-associated phosphatase, CDKN3, CDI1, CIP2, KAP
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7528b was selected from the C-term region of human CDKN3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDKN3
Synonyms CDI1, CIP2, KAP
Function May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. Dephosphorylates CDK2 at 'Thr-160' in a cyclin-dependent manner.
Cellular Location Cytoplasm, perinuclear region
Research Areas
Citations (0)

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CDKN3 belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. The gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers.


Yeh, C.T., et al., Biochem. Biophys. Res. Commun. 305(2):311-314 (2003).Yeh, C.T., et al., Cancer Res. 60(17):4697-4700 (2000).Lee, S.W., et al., Mol. Cell. Biol. 20(5):1723-1732 (2000).Poon, R.Y., et al., Science 270(5233):90-93 (1995).Hannon, G.J., et al., Proc. Natl. Acad. Sci. U.S.A. 91(5):1731-1735 (1994).

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$ 80.00
Cat# BP7528b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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