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CLK3 Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P49761
Clone Names 3011304
Peptide ID 3011304
Additional Information
Gene ID 1198
Other Names Dual specificity protein kinase CLK3, CDC-like kinase 3, CLK3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7531a was selected from the N-term region of human CLK3 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format The synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CLK3
Function Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.
Cellular Location Isoform 1: Nucleus. Cytoplasm. Cytoplasmic vesicle, secretory vesicle, acrosome
Tissue Location Endothelial cells.
Research Areas
Citations (0)

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This gene encodes a protein belonging to the serine/threonine type protein kinase family. This protein is a nuclear dual-specificity kinase that regulates the intranuclear distribution of the serine/arginine-rich (SR) family of splicing factors. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. Pseudogenes located on chromosomes 1 and 9 have been found for this gene.


Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).Hanes, J., et al., J. Mol. Biol. 244(5):665-672 (1994).

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$ 80.00
Cat# BP7531a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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