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>   home   >   Products   >   Peptides   >   Blocking Peptides   >   MAPK15 Antibody (Center) Blocking peptide   

MAPK15 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q8TD08
Clone Names 70411271
Additional Information
Gene ID 225689
Other Names Mitogen-activated protein kinase 15, MAP kinase 15, MAPK 15, Extracellular signal-regulated kinase 7, ERK-7, Extracellular signal-regulated kinase 8, ERK-8, MAPK15, ERK7, ERK8
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7554c was selected from the Center region of human ERK8. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name MAPK15
Synonyms ERK7, ERK8
Function In vitro, phosphorylates MBP.
Tissue Location Widely expressed with a maximal expression in lung and kidney.
Research Areas
Citations (0)

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The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions.


Saelzler,M.P., J. Biol. Chem. 281 (24), 16821-16832 (2006)Iavarone,C., J. Biol. Chem. 281 (15), 10567-10576 (2006)Klevernic,I.V., Biochem. J. 394 (PT 1), 365-373 (2006)Suzuki,Y., Genome Res. 14 (9), 1711-1718 (2004)

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$ 80.00
Cat# BP7554c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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