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CBR1 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P16152
Clone Names 80102154
Peptide ID 80102154
Additional Information
Gene ID 873
Other Names Carbonyl reductase [NADPH] 1, 15-hydroxyprostaglandin dehydrogenase [NADP(+)], NADPH-dependent carbonyl reductase 1, Prostaglandin 9-ketoreductase, Prostaglandin-E(2) 9-reductase, CBR1, CBR, CRN
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7563b was selected from the C-term region of human CBR1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CBR1
Synonyms CBR, CRN, SDR21C1
Function NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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Carbonyl reductase 1 (CBR1)is one of several monomeric,NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues.


Colombe,L.,Exp. Dermatol. 16 (9), 762-769 (2007)Lakhman,S.S.,Mol. Pharmacol. 72 (3), 734-743 (2007)Gonzalez-Covarrubias,V.,Drug Metab. Dispos. 35 (6), 973-980 (2007)

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$ 80.00
Cat# BP7563b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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