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EPRS Antibody (N-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P07814
Clone Names 71228113
Peptide ID 71228113
Additional Information
Gene ID 2058
Other Names Bifunctional glutamate/proline--tRNA ligase, Bifunctional aminoacyl-tRNA synthetase, Cell proliferation-inducing gene 32 protein, Glutamatyl-prolyl-tRNA synthetase, Glutamate--tRNA ligase, Glutamyl-tRNA synthetase, GluRS, Proline--tRNA ligase, Prolyl-tRNA synthetase, EPRS, GLNS, PARS, QARS, QPRS
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7565a was selected from the N-term region of human EPRS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Catalyzes the attachment of the cognate amino acid to the corresponding tRNA in a two-step reaction: the amino acid is first activated by ATP to form a covalent intermediate with AMP and is then transferred to the acceptor end of the cognate tRNA. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the multisynthetase complex and assembles into the GAIT complex which binds to stem loop- containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. EPRS is a multifunctional aminoacyl-tRNA synthetase that catalyzes the aminoacylation of glutamic acid and proline tRNA species.


Jia,J., Mol. Cell 29 (6), 679-690 (2008)Beausoleil,S.A., Nat. Biotechnol. 24 (10), 1285-1292 (2006)Kato,T., Cancer Res. 65 (13), 5638-5646 (2005)Sampath,P., Cell 119 (2), 195-208 (2004)

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$ 80.00
Cat# BP7565a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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