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Aromatase (CYP19A1) Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P11511
Clone Names 80102170
Peptide ID 80102170
Additional Information
Gene ID 1588
Other Names Aromatase, CYPXIX, Cytochrome P-450AROM, Cytochrome P450 19A1, Estrogen synthase, CYP19A1, ARO1, CYAR, CYP19
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7571b was selected from the C-term region of human CYP19A1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CYP19A1
Synonyms ARO1, CYAR, CYP19
Function Catalyzes the formation of aromatic C18 estrogens from C19 androgens.
Cellular Location Membrane; Peripheral membrane protein.
Tissue Location Brain, placenta and gonads.
Research Areas
Citations (0)

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CYP19A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis, three successive hydroxylations of the A ring of androgens. Mutations in the gene encoding CYP19A1 can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation.


Xita,N.,Eur. J. Endocrinol. 158 (6), 861-865 (2008)Dos Santos,R.M.,(er) DNA Cell Biol. (2008) In pressNelson,D.R.,Pharmacogenetics 14 (1), 1-18 (2004)

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$ 80.00
Cat# BP7571b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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