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RASGRF1 Antibody (S929) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q13972
Clone Names 109209
Peptide ID 109209
Additional Information
Gene ID 5923
Other Names Ras-specific guanine nucleotide-releasing factor 1, Ras-GRF1, Guanine nucleotide-releasing protein, GNRP, Ras-specific nucleotide exchange factor CDC25, RASGRF1, CDC25, GNRP, GRF1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7582b was selected from the S929 region of human RASGRF1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name RASGRF1
Synonyms CDC25, GNRP, GRF1
Function Promotes the exchange of Ras-bound GDP by GTP.
Research Areas
Citations (0)

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Background

RASGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. Studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory.

References

Iguchi,T., Int. J. Oncol. 31 (2), 285-291 (2007)Holmes,R., Mol. Cell. Biol. 26 (24), 9564-9570 (2006)

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$ 80.00
Cat# BP7582b
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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