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APOA4 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P06727
Other Accession A8MSL6
Clone Names 80118122
Additional Information
Gene ID 337
Other Names Apolipoprotein A-IV, Apo-AIV, ApoA-IV, Apolipoprotein A4, APOA4
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7591a was selected from the N-term region of human APOA4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name APOA4
Function May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.
Cellular Location Secreted.
Tissue Location Synthesized primarily in the intestine and secreted in plasma
Research Areas
Citations (0)
citation

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Background

The primary translation product of the APOA4 gene is a 396-residue preprotein which after proteolytic processing is secreted into its primary site of synthesis, the intestine, in association with chylomicron particles. Although its precise function is not known, apo A-IV is a potent activator of lecithin-cholesterol acyltransferase in vitro.

References

Chien,K.L., Clin. Chim. Acta 388 (1-2), 78-83 (2008)Bai,H., Acta Cardiol 63 (3), 315-322 (2008)

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$ 277.78
Cat# BP7591a
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