|Other Names||Disheveled-associated activator of morphogenesis 2, DAAM2, KIAA0381|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7595a was selected from the N-term region of humanAM2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Expressed in most tissues examined.|
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Provided below are standard protocols that you may find useful for product applications.
DAAM2 is a 1068 amino acis protein belonging to the formin homology family. It contains one of each DAD (diaphanous autoregulatory), FH1 (formin homology 1), FH2 (formin homology 2) and GBD/FH3 (Rho GTPase-binding/formin homology 3) domain. Its main function is actin cytoskeleton organization, thus leading to cell organization and biogenesis. It plays a role in Rho GTPase binding and is expressed mostly in spinal cord and nerve tissues.
Katoh,M., Int. J. Oncol. 22 (4), 915-920 (2003)
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