|Other Names||G2/mitotic-specific cyclin-B1, CCNB1, CCNB|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7598b was selected from the S126 region of human Cyclin B1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Essential for the control of the cell cycle at the G2/M (mitosis) transition.|
|Cellular Location||Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Cyclin B1 is a regulatory protein involved in mitosis. It complexes with p34(cdc2) to form the maturation-promoting factor (MPF).
Yoshida, T., et al., Ann. Oncol. 15(2):252-256 (2004).Chang, D.C., et al., J. Biol. Chem. 278(39):37865-37873 (2003).Sanchez, V., et al., J. Virol. 77(24):13214-13224 (2003).Li, J.Q., et al., Int. J. Oncol. 22(5):1101-1110 (2003).Porter, L.A., et al., Blood 101(5):1928-1933 (2003).
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