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LUM Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P51884
Clone Names 80917047
Additional Information
Gene ID 4060
Other Names Lumican, Keratan sulfate proteoglycan lumican, KSPG lumican, LUM, LDC, SLRR2D
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7605a was selected from the N-term region of human LUM. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name LUM
Synonyms LDC, SLRR2D
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Cornea and other tissues.
Research Areas
Citations (0)
citation

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Background

LUM encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, this protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. The protein is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.

References

Wang,P., Li,S. Invest. Ophthalmol. Vis. Sci. 50 (4), 1546-1551 (2009)Matsuda,Y., Yamamoto,T. Int. J. Oncol. 33 (6), 1177-1185 (2008)Kelemen,L.E., Couch,F.J. Breast Cancer Res. 10 (6), R98 (2008)

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$ 277.78
Cat# BP7605a
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Availability: 2 weeks
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