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IGFBP3 Antibody (S183) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P17936
Clone Names 80130212
Peptide ID 80130212
Additional Information
Gene ID 3486
Other Names Insulin-like growth factor-binding protein 3, IBP-3, IGF-binding protein 3, IGFBP-3, IGFBP3, IBP3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7641d was selected from the S183 region of human IGFBP3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms IBP3
Function IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.
Cellular Location Secreted.
Tissue Location Expressed by most tissues. Present in plasma.
Research Areas
Citations (0)

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IGFBP3 is a member of the insulin-like growth factor binding protein (IGFBP) family with an IGFBP domain and a thyroglobulin type-I domain. This protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors.


Muzumdar,R.H., Diabetes 55 (10), 2788-2796 (2006)Novosyadlyy,R., Growth Horm. IGF Res. 15 (5), 313-323 (2005)

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$ 80.00
Cat# BP7641d
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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