|Other Names||Sestrin-1, p53-regulated protein PA26, SESN1, PA26, SEST1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7650b was selected from the C-term region of human Sestrin-1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the reduction of peroxiredoxins. May also be regulator of cellular growth.|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
Sestrin-1 is involved in the reduction of peroxiredoxins. This protein may also be regulator of cellular growth.
Budanov,A.V., Science 304 (5670), 596-600 (2004)Peeters,H., Hum. Genet. 112 (5-6), 573-580 (2003)Velasco-Miguel,S., Oncogene 18 (1), 127-137 (1999)
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