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MPST Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P25325
Clone Names 80902034
Peptide ID 80902034
Additional Information
Gene ID 4357
Other Names 3-mercaptopyruvate sulfurtransferase, MST, MPST, TST2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7652b was selected from the C-term region of human MPST. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms TST2
Function Transfer of a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. Detoxifies cyanide and is required for thiosulfate biosynthesis. Acts as an antioxidant. In combination with cysteine aminotransferase (CAT), contributes to the catabolism of cysteine and is an important producer of hydrogen sulfide in the brain, retina and vascular endothelial cells. Hydrogen sulfide H(2)S is an important synaptic modulator, signaling molecule, smooth muscle contractor and neuroprotectant. Its production by the 3MST/CAT pathway is regulated by calcium ions (By similarity).
Cellular Location Cytoplasm. Mitochondrion. Cell junction, synapse, synaptosome
Research Areas
Citations (0)

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MPST catalyzes the transfer of a sulfur ion from 3-mercaptopyruvate to cyanide or other thiol compounds. It may be involved in cysteine degradation and cyanide detoxification. There is confusion in literature between this protein (mercaptopyruvate sulfurtransferase, MPST), which appears to be cytoplasmic, and thiosulfate sulfurtransferase (rhodanese, TST), which is a mitochondrial protein. Deficiency in MPST activity has been implicated in a rare inheritable disorder known as mercaptolactate-cysteine disulfiduria (MCDU).


Billaut-Laden,I., Toxicol. Lett. 165 (2), 101-111 (2006)

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$ 80.00
Cat# BP7652b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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