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ROR1 Antibody Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q01973
Additional Information
Gene ID 4919
Other Names Tyrosine-protein kinase transmembrane receptor ROR1, Neurotrophic tyrosine kinase, receptor-related 1, ROR1, NTRKR1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7671d was selected from the region of human ROR1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ROR1
Synonyms NTRKR1
Function Tyrosine-protein kinase receptor whose role is not yet clear.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm
Research Areas
Citations (0)

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Background

ROR1 is a receptor protein tyrosine kinase whose cellular role has not been determined. It is a type I membrane protein and belongs to the ROR subfamily of cell surface receptors. Studies of a similar protein in mouse suggest that this protein may interact with another receptor protein tyrosine kinase and may be involved in skeletal and cardiac development.

References

Nomi, M., et al., Mol. Cell. Biol. 21(24):8329-8335 (2001).Reddy, U.R., et al., Genomics 41(2):283-285 (1997).Reddy, U.R., et al., Oncogene 13(7):1555-1559 (1996).Masiakowski, P., et al., J. Biol. Chem. 267(36):26181-26190 (1992).

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$ 80.00
Cat# BP7671d
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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