LECT2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O14960 |
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Clone Names | 6072335 |
Gene ID | 3950 |
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Other Names | Leukocyte cell-derived chemotaxin-2, LECT-2, hLECT2, LECT2 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7732a was selected from the N-term region of human LECT2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | LECT2 |
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Function | Has a neutrophil chemotactic activity. Also a positive regulator of chondrocyte proliferation (PubMed:9524238). Does not show metalloendopeptidase activity (PubMed:27334921). |
Cellular Location | Cytoplasm. Secreted |
Tissue Location | Highly expressed in adult and fetal liver and weakly in testis. Not expressed in bone marrow |
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Provided below are standard protocols that you may find useful for product applications.
Background
LECT2 is a secreted, 16 kDa protein that acts as a chemotactic factor to neutrophils and stimulates the growth of chondrocytes and osteoblasts. This protein has high sequence similarity to the chondromodulin repeat regions of the chicken myb-induced myeloid 1 protein. A polymorphism in the LECT2 gene may be associated with rheumatoid arthritis.
References
Sato,Y., Transplant. Proc. 36 (8), 2359-2361 (2004)Ito,M., J. Biomol. NMR 29 (4), 543-544 (2004)Ovejero,C., Hepatology 40 (1), 167-176 (2004)
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