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SLC28A2 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q62773
Additional Information
Gene ID 60423
Other Names Sodium/nucleoside cotransporter 2, Concentrative nucleoside transporter 2, CNT 2, rCNT2, Na(+)/nucleoside cotransporter 2, Sodium-coupled nucleoside transporter 2, Sodium/purine nucleoside cotransporter, SPNT, Solute carrier family 28 member 2, Slc28a2, Cnt2, Spnt
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7738b was selected from the C-term region of human SLC28A2 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name Slc28a2
Synonyms Cnt2, Spnt {ECO:0000303|PubMed:7775409}
Function Sodium-dependent and purine-selective (PubMed:7775409, PubMed:8967974, PubMed:1315767). Exhibits the transport characteristics of the nucleoside transport system cif or N1 subtype (N1/cif) (selective for purine nucleosides and uridine) (PubMed:7775409, PubMed:8967974, PubMed:1315767). Accepts purine, analogs of purine nucleosides and uridine, and exhibits high affinity for adenosine (PubMed:7775409). May contribute to regulate the transport of organic compounds in testes across the blood-testis-barrier (By similarity).
Cellular Location Membrane {ECO:0000250|UniProtKB:O43868}; Multi- pass membrane protein. Apicolateral cell membrane {ECO:0000250|UniProtKB:O43868}; Multi-pass membrane protein
Tissue Location Expressed in liver (in bile canalicular membrane vesicles (CMV) but not in sinusoidal vesicles), jejunum, spleen and heart (PubMed:7775409). Also expressed in brain and skeletal muscle (PubMed:7775409). Not expressed in kidney, muscle and lung (PubMed:7775409).
Research Areas
Citations (0)
citation

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Background

SLC28A2 regulates adenosine transport across the blood-brain barrier into the brain.

References

Li,L., Pharmacogenet. Genomics 17 (9), 783-786 (2007)

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$ 277.78
Cat# BP7738b
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Availability: 2 weeks
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