MRAS Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | O14807 |
---|---|
Clone Names | 71211137 |
Gene ID | 22808 |
---|---|
Other Names | Ras-related protein M-Ras, Ras-related protein R-Ras3, MRAS, RRAS3 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7748b was selected from the C-term region of human MRAS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | MRAS |
---|---|
Synonyms | RRAS3 |
Function | Serves as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Activates the MAP kinase pathway. |
Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side |
Tissue Location | Expression highly restricted to the brain and heart |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Members of the RAS superfamily of GTP-binding proteins, which includes MRAS, are membrane-anchored, intracellular signal transducers responsible for a variety of normal cellular functions. They are oncogenically activated in a significant fraction of tumors.
References
Yoshikawa,Y., Mol. Biol. Cell 18 (8), 2949-2959 (2007)Mitin,N.Y., J. Biol. Chem. 279 (21), 22353-22361 (2004)Kimmelman,A.C., Mol. Cell. Biol. 22 (16), 5946-5961 (2002)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.