|Other Names||Neurotrophin-4, NT-4, Neurotrophin-5, NT-5, Neutrophic factor 4, NTF4, NTF5|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7765b was selected from the C-term region of human NTF5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Target-derived survival factor for peripheral sensory sympathetic neurons.|
|Tissue Location||Highest levels in prostate, lower levels in thymus, placenta, and skeletal muscle. Expressed in embryonic and adult tissues|
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Provided below are standard protocols that you may find useful for product applications.
NTF5 is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.
Truzzi,F., J. Invest. Dermatol. 128 (8), 2031-2040 (2008)Harel,S., Mol. Hum. Reprod. 12 (6), 357-365 (2006)
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