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CAV1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q03135
Peptide ID 27049
Additional Information
Gene ID 857
Other Names Caveolin-1, CAV1, CAV
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CAV1
Synonyms CAV
Function May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)- mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3- dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
Cellular Location Golgi apparatus membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein Membrane, caveola; Peripheral membrane protein. Membrane raft Note=Colocalized with DPP4 in membrane rafts. Potential hairpin- like structure in the membrane. Membrane protein of caveolae
Tissue Location Expressed in muscle and lung, less so in liver, brain and kidney
Research Areas
Citations (0)

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CAV1 is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex.


Moore, J., et al. JAMA 303(13):1282-1287(2010)Kim, C.A., et al. J. Clin. Endocrinol. Metab. 93(4):1129-1134(2008)Olsen, J.V., et al. Cell 127(3):635-648(2006)

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$ 80.00
Cat# BP7767c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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