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CAMKK1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8N5S9 |
|---|---|
| Clone Names | 80305154 |
| Gene ID | 84254 |
|---|---|
| Other Names | Calcium/calmodulin-dependent protein kinase kinase 1, CaM-KK 1, CaM-kinase kinase 1, CaMKK 1, CaM-kinase IV kinase, Calcium/calmodulin-dependent protein kinase kinase alpha, CaM-KK alpha, CaM-kinase kinase alpha, CaMKK alpha, CAMKK1, CAMKKA |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP7768c was selected from the Center region of human CAMKK1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | CAMKK1 |
|---|---|
| Synonyms | CAMKKA |
| Function | Calcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4. Involved in regulating cell apoptosis. Promotes cell survival by phosphorylating AKT1/PKB that inhibits pro-apoptotic BAD/Bcl2- antagonist of cell death. |
| Cellular Location | Cytoplasm. Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
CAMKK1 belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade.
References
Guest,C.B., PLoS ONE 3 (2), E1606 (2008)Rudd,M.F., Genome Res. 16 (6), 693-701 (2006)Ishikawa,Y., FEBS Lett. 550 (1-3), 57-63 (2003)Matsushita,M., J. Biol. Chem. 274 (15), 10086-10093 (1999)
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