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NGFB Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession P01138
Clone Names 71211138
Peptide ID 71211138
Additional Information
Gene ID 4803
Other Names Beta-nerve growth factor, Beta-NGF, NGF, NGFB
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7771c was selected from the Center region of human NGFB. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name NGF
Synonyms NGFB
Function Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).
Cellular Location Secreted.
Research Areas
Citations (0)

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NGFB is a member of the NGF-beta family. It is a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in the gene encoding NGFB have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of the gene's expression is associated with allergic rhinitis.


Lang,U.E., Pharmacopsychiatry 41 (5), 196-199 (2008)Truzzi,F., J. Invest. Dermatol. 128 (8), 2031-2040 (2008)MacGrogan,D., J. Neurochem. 59 (4), 1381-1391 (1992)

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$ 80.00
Cat# BP7771c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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