|Other Names||Latent-transforming growth factor beta-binding protein 1, LTBP-1, Transforming growth factor beta-1-binding protein 1, TGF-beta1-BP-1, LTBP1|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP7780a was selected from the N-term region of human LTBP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM).|
|Tissue Location||Expressed in the aorta (at protein level). Isoform Long is found in fibroblasts|
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Provided below are standard protocols that you may find useful for product applications.
This protein may be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM).
Olofsson A., J. Biol. Chem. 270:31294-31297(1995)Kanzaki T., Cell 61:1051-1061(1990)Isogai Z., J. Biol. Chem. 278:2750-2757(2003)Oklu R., Biochem. J. 352:601-610(2000)
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