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LTBP1 Antibody (N-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q14766
Clone Names 71213137
Peptide ID 71213137
Additional Information
Gene ID 4052
Other Names Latent-transforming growth factor beta-binding protein 1, LTBP-1, Transforming growth factor beta-1-binding protein 1, TGF-beta1-BP-1, LTBP1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP7780a was selected from the N-term region of human LTBP1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name LTBP1
Function May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM).
Cellular Location Secreted.
Tissue Location Expressed in the aorta (at protein level). Isoform Long is found in fibroblasts
Research Areas
Citations (0)

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Background

This protein may be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM).

References

Olofsson A., J. Biol. Chem. 270:31294-31297(1995)Kanzaki T., Cell 61:1051-1061(1990)Isogai Z., J. Biol. Chem. 278:2750-2757(2003)Oklu R., Biochem. J. 352:601-610(2000)

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$ 80.00
Cat# BP7780a
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