IRS2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9Y4H2 |
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Gene ID | 8660 |
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Other Names | Insulin receptor substrate 2, IRS-2, IRS2 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | IRS2 |
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Function | May mediate the control of various cellular processes by insulin. |
Cellular Location | Cytoplasm, cytosol. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
References
Barbieri, M., et al. J. Gerontol. A Biol. Sci. Med. Sci. 65(3):282-286(2010)Craig, D.W., et al. Diabet. Med. 26(11):1090-1098(2009)Rikova, K., et al. Cell 131(6):1190-1203(2007)
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